Soft Tissue Attachments (STAs) cause significant morbidity

• STAs occur after nearly all abdominal procedures (1) and complications include
  chronic pain, infertility, impaired organ function, small bowel obstruction and
  riskier, more difficult re-operations (2)
• 33% of patients with previous surgeries are usually readmitted twice for
  STA-related complications (3)
• Post-operative STAs are now the leading cause of bowel obstruction (4)
• Even the best surgical techniques won’t prevent STAs from occurring in the
  majority of cases

SurgiWrap® is designed to effectively reduce STAs

• PLA has no clinically significant side effects and has been used safely for more than 35 years in a wide variety of medical devices
• Contains no human or animal components, avoiding the risk of severe immunogenecity and disease transmission

Peritoneal Healing and Tissue Attachment (5)

Initially after surgical injury of the peritoneum or serosa an increased vascular permeability occurs which produces an inflammatory exudate and forms a fibrin matrix.

Surgical sites that have had the additional trauma of cauterization, laser, or other treatments involved with the development of carbon particles have shown extended healing times greater than two weeks. (5,6) The need for a mechanism to support the soft tissues throughout this prolonged healing process is evident in areas where such trauma has occurred. (5,6)

Surgical Solution

Besides the surgical principles in handling serosal tissue, the accepted solution for minimizing/
reducing post-operative attachments is to physically separate the opposing tissues throughout the critical healing process. Thus the tissue may regenerate without interconnective attachments.

 
References

1. Ellis H. The clinical significance of adhesions: focus on intestinal obstruction. Eur J Surg Suppl. 1997;577:5-9

2. Diamond MP, Freeman ML. Clinical implications of postsurgical adhesions. Hum Reprod Update. 2001;7(6):567-576.
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3. Cheong YC, Laird SM, Li TC, et al. Peritoneal healing and adhesion formation/reformation. Hum Reprod Update. 2001;7(6):556-566.

4. Tulundi T. Minisymposium on post-surgical adhesions introduction-prevention of adhesion formation: the journey continues. Hum Reprod Update. 2001;7(6):545-546.

5 diZeraga GS. Peritoneum, Peritoneal healing, and Adhesion Formation New York: Springer-Verlag 2000

6 Elkins TE, Stovall TG, Warren J, Ling FW, and Meyer, NL: A Histologic Evaluation of Peritoneal Injury and Repair: Implications for Adhesion Formation. Obstetrics & Gynecology 70(2): 225-228, 1987
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See other related information:

• Biomaterials
• USA Products & Services
• Literature
• Soft Tissue Repair

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